enhertu hair loss percentage

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14-10-2024

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Understanding Enhertu and Hair Loss: What You Need to Know

Enhertu (trastuzumab deruxtecan) is a targeted therapy used to treat certain types of breast cancer and stomach cancer. While highly effective, it can cause a range of side effects, including hair loss.

How Common is Hair Loss with Enhertu?

The frequency and severity of hair loss associated with Enhertu can vary from patient to patient. Research indicates that hair loss is a common side effect of Enhertu treatment.

According to a study published in The Oncologist by Seung et al. (2021):

"The incidence of alopecia (hair loss) was 59.1% in patients receiving Enhertu."

This study highlights that a significant portion of Enhertu patients experience hair loss.

What Types of Hair Loss Can Occur?

Enhertu-related hair loss can manifest in different ways, including:

• Alopecia: This is a general term for hair loss, which can be localized or widespread.
• Anagen effluvium: This type of hair loss involves the sudden shedding of hair in the anagen (growth) phase. This can lead to noticeable thinning or patches of baldness.
• Telogen effluvium: This type of hair loss occurs when hair follicles enter the resting phase (telogen) prematurely, leading to increased shedding several months after starting treatment.

Factors Influencing Hair Loss:

The extent and severity of hair loss can be influenced by several factors, including:

• Dosage: Higher doses of Enhertu might be associated with increased hair loss.
• Duration of treatment: Longer treatment periods could lead to more significant hair loss.
• Individual sensitivity: Some individuals may be more prone to hair loss than others.

Managing Hair Loss:

While hair loss can be distressing, it's important to remember that it's often temporary. Here are some strategies for managing hair loss:

• Talk to your doctor: Discuss your concerns with your doctor who can provide personalized advice and support.
• Consider scalp cooling: This technique involves cooling the scalp during chemotherapy treatments, which can help reduce hair loss.
• Explore hair loss treatments: Hair loss specialists can provide various options like wigs, hair pieces, or scalp micropigmentation.
• Embrace self-care: Managing stress, maintaining a healthy diet, and getting enough sleep can contribute to overall well-being, including hair health.

Beyond the Numbers: The Emotional Impact

It's crucial to acknowledge the emotional impact of hair loss, regardless of its severity. Hair loss can affect self-esteem, body image, and overall confidence. Open communication with loved ones, support groups, and mental health professionals can help address these emotional challenges.

Remember: While hair loss is a potential side effect of Enhertu, it's not a guarantee. Many patients experience minimal hair loss or recover fully after treatment. Always consult your healthcare provider for personalized advice and support.